Surname John Isaac (John Isaac 
) , in the world, is a very rare cognomen. The last name John Isaac is characteristic of Latin America and the Caribbean, particularly Chile, where it is a very rare surname. More frequently, John Isaac is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| John Isaac | Philippines, Peru, Germany, Chile, Ecuador |
Cho, Aguilar, Casulla, Camacho, Coggins, Baculio, Palileo, Delgado, Juliano, Henares, Sta Ana, Hilario, Sta. Ana, Abadines, Castillo, Calderon, Barranco, Wattimena, San Gregorio, Natividad, Hjalmarson, Fabiani, Sanchez, Manwell, Mariano, Bio, Caga, Buco, Kung, Ward, Merin, Mejia, Borja, Bohol, Paran, Reyes, Lugtu, Marcos, Medina, Aballe, Pasion, Dumlao, Laroya, Torres, Edades, Flores, Concepcion, and Muñoz Carrillo